Kazuo Ishiguro Wins Nobel Prize for Literature

British novelist Kazuo Ishiguro, best known for his book “The Remains of the Day,” has been awarded the 2017 Nobel Prize for Literature, the Swedish Academy said.

Ishiguro, “in novels of great emotional force, has uncovered the abyss beneath our illusory sense of connection with the world,” the Academy wrote.

The prize is worth 9 million kronor ($1.1 million).

A revolutionary technique dubbed cryo-electron microscopy, which has peered closer at the Zika virus and an Alzheimer’s enzyme, earned scientists Jacques Dubochet, Joachim Frank and Richard Henderson the Nobel Chemistry Prize on Wednesday.

Thanks to the international team’s “cool method”, which uses electron beams to examine the tiniest structures of cells, “researchers can now freeze biomolecules mid-movement and visualise processes they have never previously seen,” the Nobel chemistry committee said.

This has been “decisive for both the basic understanding of life’s chemistry and for the development of pharmaceuticals,” it added. 

The ultra-sensitive imaging method allows molecules to be flash-frozen and studied in their natural form, without the need for dyes.

It has laid bare never-before-seen details of the tiny protein machines that run all cells.

Climate Change Threatens Flights Worldwide

London- Climate change will significantly increase the incidence of severe turbulence worldwide, a new study has found.

The study, which was published in the journal Geophysical Research Letters, said that severe mid-flight turbulence could triple by 2050.

Researchers from the University of Reading have created a mathematical model to predict how clear-air turbulence (CAT) – the most troublesome type – will be affected by global conditions from 2050-2080.

They said CAT, which is invisible and can’t be see on radars, is strong enough to throw people and luggage around an aircraft cabin.

At a typical cruising altitude of 39,000 feet, the study found severe turbulence will be 180 percent more common over the North Atlantic, 160 percent more common over Europe, 110 percent over North America, 90 percent over the North Pacific, and 60 percent over Asia.

The Southern Hemisphere will also experience an increase, though less than in the Northern Hemisphere. The skies over South America will experience a 60 percent increase in severe turbulence, Australia 50 percent, and Africa 50 percent.

Luke Storer, a PhD researcher who worked on the study, said: “While turbulence does not usually pose a major danger to flights, it is responsible for hundreds of passenger injuries every year.”

Premier League: 10 Talking Points from the Weekend’s Action

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London – 1) Hughton hankers after firepower

Chris Hughton, the Brighton & Hove Albion manager, said it all when he highlighted how his team had not been “out of sight” against Arsenal, just as they had not been against Manchester City on the opening weekend of the season. On both occasions, the final scoreline of 0-2 hinted at respectability. Which, in truth, was Brighton’s priority. The gap to the Premier League’s top six clubs yawns like a chasm and Hughton’s approach at the Emirates Stadium – an approach born out of necessity – was characterised by damage limitation. Hughton used a 4-5-1 system and, even after Nacho Monreal’s early opener, Brighton did not come out. Their lack of firepower remains a worry. It was the fourth time in seven league matches that they had drawn a blank. However, their season will not be defined by away games like this. David Hytner

2) Vardy’s body needs some respite

After an uneasy start to the season, in which Leicester City have earned a meagre five points, Craig Shakespeare can find some respite before they host West Bromwich Albion on 16 October. The same applies for Jamie Vardy – omitted from the England squad – who will be given a steroid injection to solve his hip problem this week. His manager defended the striker’s decision to play through the pain barrier for his club but not country. “The idea for us and for England is he comes back once he’s had that little bit of a break raring to go again,” Shakespeare said, adding that medical staff from both parties had discussed the issue. “It’s never been questioned, Jamie wants to play for England and for Leicester. The time now: it’s right to give him this break, just to give a little bit of a rest, to fully recover from this injury.” Ben Fisher

3) Conte needs to find a plan B

Antonio Conte returns home to Italy for a few days over the international window seeking “a rest”, but he will spend the next fortnight stewing on the defeat to Manchester City. He has retained a league title as a manager before, though never in a division where the elite are quite this reinforced. At Juventus in 2012 he had been braced for a renewed challenge from Milan. “But, instead, they sold Zlatan Ibrahimovic and Thiago Silva to Paris Saint-Germain, so they became weaker,” he said. “It wasn’t simple second time, but it was easier. Here, from last season to this, you have big teams becoming bigger.” Manchester City demonstrated as much at Chelsea’s expense on Saturday, and Manchester United, only off the top on goal difference, appear just as imposing. Therein lies the justification for Conte’s frustration, aired within Stamford Bridge over the summer, at the need for more significant squad strengthening to keep ahead of the rest. The head coach always knew life was going to be harder this time round. Saturday proved it. Dominic Fifield

4) Everton need to go back to basics

Everton’s struggles continue. While not replacing Romelu Lukaku’s clinical finishing is obviously a problem so, too, is Ronald Koeman’s defence. Michael Keane was signed in the summer from Burnley for £30m. But statuesque defending made Burnley look more like Barcelona as they combined for a total of 24 passes through nine players for Jeff Hendrick to apply the finishing touch past Jordan Pickford. Morgan Schneiderlin allowed Hendrick to ease past him, leaving Pickford stranded, and the lack of desire from the Frenchman and the unit as a whole shows a defence badly out of form. At this stage last season Everton had conceded four goals and kept three clean sheets. They have now conceded 12. If Koeman cannot bring his side back to basing their success on being difficult to beat then, regardless of how well his expensive attacking force play, Everton will continue the struggle. Graham Searles

5) Huddersfield crash back down to earth

Amid a cornucopia of perks, the downside to being a footballer is that you have to do your growing-up in public. So far in his short career Dele Alli has attracted derision for some naughty challenges, a rude gesture and, on Saturday against Huddersfield Town, a devious dive. Those deeds were varying degrees of bad. But if they are the worst things that this 21-year-old has done while rising to the top of a fiercely competitive profession, and if he learns from them, then who among us can honestly hold them against him for long? As for Huddersfield, they entered this match with the second best defensive record in the Premier League, but ended with their first home defeat in the league this season. “They’re one of the best teams in the league. You could tell that,” the Huddersfield midfielder Aaron Mooy said after the defeat. Paul Doyle

6) Hodgson wants his players to show their mettle

Crystal Palace’s hammering at Manchester United makes it seven defeats from as many Premier League games, 17 goals conceded and none scored. Chelsea visit Selhurst Park on 14 October. So, how is the spirit among Roy Hodgson’s players? “It’s been excellent,” he said. “Obviously, it’s going to get more fractious because we put our messages across quite strongly and there will be some on the field who don’t pick up those messages as quickly as others. But that’s nothing I can’t deal with.” Yet the manager will again be without three key figures for Chelsea’s visit. “[Christian] Benteke won’t be back for a few weeks, so we still won’t have a recognised centre forward. Wilf Zaha probably won’t be back [each has a knee problem]. Ruben Loftus-Cheek [ineligible] can’t play. So it’s got to be the lads I put out there who go out there and run their bollocks off, if you excuse my expression, to try to do the best job they can possibly do,” Hodgson says. It may get worse before it gets any better. Jamie Jackson

7) Lack of finishing power haunting Klopp’s men

Time was when Newcastle v Liverpool was a match anticipated like no other. Two aggressive teams who were seemingly interested only in attacking and with centre-forwards who could be relied upon to deliver in front of goal. The thing is that time was more than 20 years ago. While Liverpool’s aspirations have not changed much in that time, namely a first league title since 1990, Newcastle had to recalibrate theirs long ago. The death of Freddy Shepherd last week, and his commemoration at this match, served as a reminder of the Magpies’ Icarus-like brush with the Premier League title in 1996. For Newcastle, this draw will have given them encouragement in their ability to hold out against better sides. For Liverpool, the failure to convert chances, once again, haunts them, like that clock that has been ticking for 27 years. Conrad Leach

8) Pellegrino needs a rethink on forward options

There is an argument that Southampton’s attackers lost so much confidence under Claude Puel last season that it will take time for Mauricio Pellegrino’s ideas to take hold. But after this defeat by Stoke City, concern is growing about Pellegrino’s flexibility. Southampton’s two wins have come against Crystal Palace and a 10-man West Ham, and scoring five goals in seven matches has not exactly set pulses racing at St Mary’s. Pellegrino has favoured a 4-2-3-1 system and Shane Long started as a lone striker against Stoke, with Charlie Austin and Manolo Gabbiadini both on the bench. Long’s tireless running can be useful in that role, but his selflessness is rendered ineffective by the inability of Southampton’s creative players to take advantage of the space created by the Irish forward. Might it be time for Pellegrino to think about pairing Long with Austin or Gabbiadini? Jacob Steinberg

9) West Brom treading water despite money spent
There was a feeling that West Brom had made some brilliant signings when the transfer window closed, and the excitement around the Hawthorns was tangible. A month later the view about Albion’s activity in the market has not changed but the same cannot be said for the mood. Albion sit 10th, which is respectable enough, but the broader picture shows only three wins from 19 league matches and, perhaps most frustratingly for the supporters, no shift in the way the team plays, despite £40m being spent. Tony Pulis is never going to ask his teams to open up and play gung-ho, but it is hard to escape the feeling that the group of players at his disposal should be capable of coming up with a better way of holding on to a 2-1 lead than time-wasting almost throughout the second half. The tactics were overly negative and came back to bite Albion when Watford scored a 95th-minute equaliser. Stuart James

10) Clement’s cupboard is bare in attack

It was always likely to be a difficult season for Swansea after the departures of Fernando Llorente and Gylfi Sigurdsson. Their combination was pivotal in Swansea’s fight to stay up and it is no surprise they are toiling without them. Paul Clement could not hide his frustration after the defeat to West Ham, which pushed Swansea into the bottom three. The manager was pleased with his team’s composed passing in midfield but he was unhappy with their decisions in the final third and critical of his forwards for their timidity. Wilfried Bony had one effort before being taken off at half-time, while Tammy Abraham and Jordan Ayew were quiet. Yet Clement must also shoulder some of the blame. Swansea created nothing at the London Stadium and three goals in seven games is damning. They lack imagination and width and will be in huge trouble if nothing changes. Jacob Steinberg

The Guardian Sport

Oxford University to Test Universal Flu Vaccine in World First

A nurse vaccinates a patient as part of the start of the seasonal influenza vaccination campaign in Nice

A seasonal flu vaccine that would be the first in the world to fight all types of the virus is to be tested in a two-year clinical trial involving more than 2,000 patients by researchers in Oxford.

The so-called universal vaccine was developed by Oxford University’s Jenner Institute and Vaccitech, a spin-out biotech company founded by Jenner scientists.

Current flu vaccines have to be changed each year to match strains of virus circulating at the time and they do not always protect people that well, especially older patients with weak immune systems.

The new vaccine works by using proteins found in the core of the virus rather than those on its surface. Surface proteins stick out like pins from the virus and change all the time, while those in the core are stable.

Significantly, the new vaccine works by stimulating the immune system to boost virus-killing T-cells, instead of antibodies. Previous research has shown such T-cells can help fight more than one type of flu virus.

Researchers hope the new vaccine will provide better and longer-lasting protection when used alongside the regular seasonal flu shot.

“We’re hoping it will last two to three years – maybe even four years – but we really don’t know until we do the trials,” Vaccitech Chief Executive Tom Evans told Reuters.

The new vaccine has already been tested for safety in earlier trials. Now it is advancing into mid-stage Phase IIb testing, which will see the recruitment of at least 500 British subjects this season. The remainder will be recruited during the 2018/9 flu season.

It is the first time a universal flu vaccine has progressed beyond Phase I clinical testing.

Assuming it is successful in Phase IIb, the new shot will still have to go into much bigger and expensive final-stage testing and Evans said the plan would be to bring in a partner at this stage of development.

“We would look for a better-capitalized company to take this into final Phase III tests,” he said.

Leading manufacturers of seasonal flu vaccines include Sanofi, GlaxoSmithKline and CSL’s Seqirus, which includes the old Novartis flu vaccine business.

Didier Deschamps: I Apply my own Style and Have Not Taken Anything from other Coaches

Deschamps

London – In an extract from a new book France manager Didier Deschamps discusses leadership, talent and creating a link with his players based on trust.

Didier Deschamps is sitting opposite me in a hotel bar in Monaco and is explaining the art of leadership. “I don’t think you just become a leader,” he says, leaning forward in a low armchair and sipping an espresso. “You can’t wake up one morning and say, ‘Right, now I’m going to be a leader.’ I think it is something that’s in you, that you’re born with, and which develops. Some people have that character, that personality and it comes naturally. You can’t force it. It has to be authentic and natural. Innate. It comes from you, your early years, your attitude as an adolescent, how you are with a group and as the one who influences things.”

In the past Deschamps has credited Aimé Jacquet (France’s World Cup-winning coach) and Marcello Lippi as great influences. He spoke of Jacquet’s man-management skills and Lippi’s tactical smarts. But when I ask what he has taken from different coaches, he snaps. “I didn’t take anything!” His fist slaps into his palm to make his point. “Everything you go through has to fit in with the way you are and your own ideas. You wouldn’t be able to do today what coaches did when I was a player. I say something to my son and he tells me I’m prehistoric. You have to live in your time, be of today.”

This is one of the key lessons that Deschamps is keen to impart. Leaders may be born but adaptability can be developed. And for managers today it could be the most important of all. Just because one plan worked at a certain time with a certain group is no guarantee that the same plan will work again elsewhere.

“The key thing is knowing how to adapt,” he says. “Adapting to the group that you have at your disposal; adapting to the place where you’re working; adapting to the local environment. This is crucial: adaptability. It means being aware of the strengths and weaknesses inside the group; being aware of all the outside factors that can influence your sphere; and adapting to all of that, then modifying what you’ve done and not being afraid to change.”

Deschamps is talking on a personal level but the same is true of today’s modern, behemoth companies. PayPal began as a cryptography company, Google used to sell its own search technology to other search engines and Facebook started out as a campus-only social network. Apple was not the first to create a smartphone, a tablet computer or a digital music player: they just did it better than others. They all adapted to capture new value in the market. Deschamps’s job is to do the same.

During his 15 years as a coach – at Monaco, Marseille, Juventus and with France – Deschamps has had to adapt. Some players in the France squad were not even born when he lifted the Jules Rimet Trophy at the Stade de France in 1998. He openly admits that managing millennials today is a challenge and not just in the sporting context.

“The role of the leader is much more complex today,” he says. “In society at large mentalities have changed. In any professional sphere an 18-year-old wants everything and they want it straightaway because they feel strong. They have mastered new technology which gives them a certain power over generations above them. And these days an 18-year-old has no qualms about wanting to take the place of someone who’s 30 or 40, who has experience. These days there are no borders; kids feel strong and confident. They have a desire to explore and to conquer. These can be good things but there can be a bad side as well.”

This often involves an entourage whose motivations may not always tally with the player’s best interests, or a social network that provides the player with a link to fans and additional commercial revenue. These are outside influences that never concerned Deschamps as a player. “They see players as a cash cow and that cow has to keep giving milk.” Deschamps gives an example of the player who has been dropped and whose agent tells him, “The coach is an idiot” and demands a move straightaway. He has seen it happen.

“One of the words I hear a lot is injustice,” he continues. “But what is considered injustice for them may not be something you agree with. So it all becomes a question of how you interpret words and where you put your cursor on the importance of words. For a lot of young guys these days, very quickly they will say that’s totally unfair.”

This may be familiar to those who work with millennials in a non-sporting environment. They are accused of being entitled, narcissistic and unfocused, attitudes that confound their managers. Social networks have created a generation who crave instant recognition. Technology empowers them to challenge authority.

Simon Sinek, a British-American author and motivational speaker, urges leaders today to understand how social media also affects behaviors. Engagement with social media releases dopamine, the same chemical triggered by smoking, drinking or gambling. Dopamine is addictive and social media gives people access to that hit. As this generation switch their craving for approval from parents to their peers, so they rely on social networks: for likes, retweets and shares.

“As they grow older we’re seeing that many kids can’t form deep-meaning relationships,” Sinek said. “Many friendships are superficial; they can’t rely on them; their friends may cancel on them. They don’t have the right coping mechanisms for stress, so when it comes in their lives they turn to a device and not to a person.”

That means a different type of management is now required. It’s one that involves an exchange of views, an understanding of opinions and a mutual trust. As Deschamps tells me how he builds that trust I am surprised by the rigor with which he approaches his role.

He thinks about every word he utters, and is acutely aware of his body language and how he delivers his message. “It’s not just about the words you use, but the way you use them, and the message that puts over. Also your face too and the way you project your message. If you’re telling the group to stay calm, be good, and you have beads of sweat dripping down your forehead, you’re in trouble …”

Deschamps takes in as much as he can. He has created a circle of trust that both empowers the group and provides him with more information to make better decisions. This is how he gains an edge.

Every new player called up to the France squad has a one-on-one chat with Deschamps. He tells them what he thinks of them, what he wants from them and warns them what to expect in the future. Once that player is an international, the way people look at him will change forever as will expectations from his support structure, team-mates, opponents and the media.

Deschamps ensures that all players have a copy of his Code of Conduct in their rooms at Clairefontaine, the French training center. In it he asks them to respect the jersey and the national anthem, to display an open and friendly attitude, to be genuine and humble and, in a section on how to handle the press, to remember that “your behavior, attitude and words shape your image as it is replayed to the public by the media, which are an unavoidable and indispensable part of your journey. They mold the image that you show to the entire country, so be professional with them, too.”

You can get a gist of his message from how Deschamps defines talent. He thinks all young players have potential, not talent. “Talent doesn’t exist in young players. Talent is something that you are able to show at a high level over a period of time. We’re talking about consistency, that’s talent. Talent has to be confirmed. It’s the confirmation of potential. It’s getting to the top and maintaining that level over a period of time.”

The player needs to understand his message. “What I don’t want them to think is that if they have to come to Clairefontaine they have made it. This is only the first step.”

Deschamps then keeps an eye on how they settle in with the squad, not just on the pitch but off it. It’s very interesting for me to watch that. Deschamps will give a youngster a wider margin for error, but he will not accept a lack of effort, a lack of determination or a lack of desire.

“If it happens they get a warning and I see how they react. It comes down to a relationship based on trust,” he says. “The role I have as national team coach is about having a moral contract. I don’t pay these guys, their club does, which is why I’m talking about a moral engagement. It’s about creating a link based on trust. The human relationships these days have become almost as important as what’s on the pitch.

“Being a manager is about recognizing talent and knowing how to use it in the right context. You need to spot that thing which tells you, ‘He’s the guy who can bring me what I need here’. Your choices are human investments; you have to put time in, to get to know them better. They have different lives, personalities, cultures, backgrounds, even views on life. So you have to be able to tune in to their station. Man-management has become extremely important.”

This is where the dialogue comes in; not always face-to-face in his office, but sometimes the odd word on the training ground or during a meal. It’s all considered and thoughtful. The information on his players is out there, available to us all. “What interests me is knowing the man behind all that.”

The Guardian Sport

Nobel Physics Prize Awarded to 3 Scientists for Proving Einstein’s ‘Gravitational Waves’ Theory

gravitational

Three scientists, whose discoveries on gravitational waves, have been awarded the 2017 Nobel Prize in Physics.

Rainer Weiss of the Massachusetts Institute of Technology and Barry Barish and Kip Thorne of the California Institute of Technology are the recipients of the award, announced by Sweden’s Royal Academy of Sciences on Tuesday.

Their discoveries in faint ripples flying through the universe called gravitational waves came as proof of a theory developed by Albert Einstein a century ago. Scientists say this fundamentally alters our understanding of the universe.

The three were key to the first observation of gravitational waves in September 2015.

When the discovery was announced several months later, it was a sensation not only among scientists but the general public.

“It’s a win for the human race as a whole. These gravitational waves will be powerful ways for the human race to explore the universe,” Thorne told The Associated Press in a phone interview.

Weiss said he hopes that eventually gravitational waves will help science learn about “the very moment when the universe came out of nothingness.”

“The best comparison is when Galileo discovered the telescope, which allowed us to see that Jupiter had moons and all of a sudden we discovered that the universe was much vaster than we used to think about. With this discovery we can study processes which were completely impossible, out of reach to us in the past,” said Ariel Goobar of the Royal Swedish Academy of Sciences.

With the technology that the three developed “We may even see entirely new objects that we haven’t even imagined yet,” said Patrick Sutton, an astronomer at Cardiff University in Wales.

Gravitational waves are extremely faint ripples in the fabric of space and time, generated by some of the most violent events in the universe.

The waves detected by the laureates came from the collision of two black holes some 1.3 billion light-years away. A light-year is about 5.88 trillion miles.

The waves were predicted by Einstein a century ago as part of his theory of general relativity. General relativity says that gravity is caused by heavy objects bending space-time, which itself is the four-dimensional way that astronomers see the universe.

The German-born Weiss was awarded half of the 9-million-kronor ($1.1 million) prize amount and Thorne and Barish will split the other half.

Weiss in the 1970s designed a laser-based device that would overcome background noise that would disturb measurements of gravitational waves. He, Thorne and Barish “ensured that four decades of effort led to gravitational waves finally being observed,” the Nobel announcement said.

The announcement said Einstein was convinced that gravitational waves could never be measured. The laureates used laser devices “to measure a change thousands of times smaller than an atomic nucleus.”

In a moment of poetry aimed at making the distant and infinitesimal phenomenon understandable to non-experts, the academy announcement said gravitational waves “are always created when a mass accelerates, like when an ice-skater pirouettes or a pair of black holes rotate around each other.”

The waves are like “a storm in the fabric of space-time that is produced when two black holes collide,” Thorne said. The first detection came from a crash 1.3 billion light-years away. A light-year is about 5.88 trillion miles.

The prize is “a win for Einstein, and a very big one,” Barish told the AP.

For the past 25 years, the physics prize has been shared among multiple winners.

Last year’s prize went to three British-born researchers who applied the mathematical discipline of topology to help understand the workings of exotic matter such as superconductors and superfluids. In 2014, a Japanese and a Canadian shared the physics prize for studies that proved that the elementary particles called neutrinos have mass.

The 2017 Nobel prizes kicked off Monday with the medicine prize being awarded to three Americans studying circadian rhythms — better known as body clocks: Jeffrey C. Hall, Michael Rosbash and Michael W. Young.

London Holds Exhibition to Highlight Scythian Culture

Scythians

London – The Scythian people, predecessors of the Mongols, ruled a massive area of the Eurasian steppe located between Northern China and the Black Sea, between the ninth and the second century B.C. Little has been known about their culture, until now.

The “Scythians: Warriors of Ancient Siberia” exhibition was launched at the British Museum in London to change the people’s perception of this ancient culture.

Back then, people feared the Scythians, calling them “warriors on horseback”. They used to drink milk from the skulls of their enemies, tattoo themselves with charcoal and consume cannabis.

The Scythians, who spoke Persian, had no written language, so information about them comes from ancient Greeks, Assyrians and Persians.

The exhibition’s website reads: “For centuries, all traces of their culture was missing, and buried under the ice.”

The exhibition, which runs until January 14, wonders whether the civilization is the inspiration behind the famous “Game of Thrones” book and television series.

Most of the 200 pieces featured in the exhibition come from southern Siberia. Many of them are borrowed from the Hermitage Museum in St. Petersburg and are being exhibited outside of Russia for the first time.

The artifacts are are well preserved because they have been buried under ice in the burial hills and tombs of the Altai Mountains in Central Asia.

The exhibit includes pieces discovered at archaeological excavations during the rule of Russia’s Peter the Great in the early 18th century. They include the head of a chief from Scythian tribal, displaying his tattooed skin and glittering gold necklaces. Other pieces include embellished gold for men and women, pendants, leather shoes, and some well-preserved pieces of cheese.

According to the German News Agency (dpa), the exhibit also features engraved stone and massive sarcophagi.

The Scythians, predecessors of the Huns and Mongols, revered horses and relied on them in their wars. Horses, adorned with heavy embellishments, were often buried with their owners to accompany them in their afterlife.

New Theme Park in Mexico to Compete with Disneyland

Mexico

London – Lovers of the ancient Mayan culture can now learn and spend a good time in a new under-construction theme park on the Caribbean coast of Mexico inspired by the civilization.

The massive project, dubbed Amikoo, or “friend” in the Mayan language, is located about 55 km south of Cancun. It will house a museum, hotel, beach resort and recreation park, according to AUSA and Gala groups for properties development.

The two companies have invested $840 million in the new amusement park in the Riviera Maya district. The park is expected to compete with the famous Disneyland.

According to the German News Agency (dpa), the first phase of the project includes a museum, a 320-room hotel, flight simulators, a diving center, a leisure center, restaurants, a surfing pool and a ballroom.

The two investing companies said that the second phase will see the establishment of a 1,200-room beach resort and a theme park by 2020.

Danish Study Finds Link between Skin Infections, Heart Attacks

London- A recent study suggests that people with psoriasis, a chronic inflammatory disease, may be more likely than others to experience heart attacks and strokes at least in part because inflammation damages their vascular system.
The analysis of tests for 190 psoriasis patients found that the longer people had lived with psoriasis, the more inflammation they had in their blood vessels.

While these imaging tests didn’t connect vascular inflammation to an increased risk of heart attacks and strokes, researchers also examined data on roughly 87,000 Danish adults with psoriasis and another 4.2 million people without the condition. They found each year people lived with psoriasis was associated with a 1% increase in the future risk of cardiovascular events like heart attacks and strokes.

According to Reuters, Lead study author Dr. Alexander Egeberg of Gentofte Hospital in Copenhagen said: “It has been suspected that long-term exposure to low-grade systemic inflammation may increase the risk of cardiovascular events, but the effect of disease duration on the relationship between psoriasis and cardiovascular disease has been unclear.”

He added that even though plenty of previous research has linked psoriasis to heart disease, the current results offer fresh evidence that living longer with systemic inflammation can increase the risk of heart attacks and strokes even for psoriasis patients who don’t have other risk factors for heart disease such as smoking, diabetes or advanced age.

The authors note in the Journal of the American Academy of Dermatology that one limitation of the study is that researchers lacked data for the Danish population on other factors that influence cardiovascular health such as obesity and exercise habits.

Legendary Rocker Tom Petty Dead at 66

Petty

Legendary US rocker Tom Petty died on Monday after suffering cardiac arrest.

The artist, who gained famed with such hits as “Refugee,” “Free Fallin’” and “American Girl,” was 66.

He was found unconscious at his home in Malibu early on Monday morning and was taken to UCLA Medical Center but could not be revived, his long-time manager Tony Dimitriades said in a statement.

“We are devastated to announce the untimely death of our father, husband, brother, leader and friend Tom Petty,” Dimitriades said on behalf of the family.

He died peacefully at 8:40 p.m. local time (0340 GMT Tuesday) surrounded by family, his bandmates and friends.

Bob Dylan called his death “shocking, crushing news” in a statement to Rolling Stone magazine.

With his vibrant guitar riffs, distinctly raw, nasal vocals and slick song lyric, Petty was best known for his roots-infused rock music. He carved a career as a solo artist as well as with his band The Heartbreakers and as part of supergroup The Traveling Wilburys.

Petty and The Heartbreakers embarked on a 40th anniversary tour of the United States this year and last played three dates in late September at the Hollywood Bowl in Los Angeles. The band was scheduled to perform two dates in New York in November.

“I’m thinking it may be the last trip around the country,” Petty told Rolling Stone last year. “We’re all on the backside of our 60s. I have a granddaughter now I’d like to see as much as I can. I don’t want to spend my life on the road. This tour will take me away for four months. With a little kid, that’s a lot of time.”

Petty formed The Heartbreakers in the mid 1970s, but it wasn’t until the band’s third album “Damn the Torpedoes” in 1979 that their music really took off, with hits such as “Refugee” and “Don’t Do Me Like That.”

He and the band were inducted into the Rock and Roll Hall of Fame in 2002, when they were described by organizers as “the quintessential American individualists”, capturing the voice of the American everyman.

“Music, as far as I have seen in the world so far, is the only real magic that I know,” Petty once said during an interview with CNN. “There is something really honest and clean and pure and it touches you in your heart.”

Petty also co-founded the 1980s supergroup The Traveling Wilburys with Dylan, Roy Orbison, George Harrison and Jeff Lynne, penning hits such as “End of the Line” and “She’s My Baby.”

Dylan said in his statement that Petty was “a great performer, full of the light, a friend, and I’ll never forget him.”

Ex-Beatle Ringo Starr wrote on Twitter: “God bless Tom Petty peace and love to his family I‘m sure going to miss you Tom.”

“I’m shocked and saddened by the news of Tom’s passing, he’s such a huge part of our musical history, there’ll never be another like him.” Eric Clapton wrote in a statement.

Petty was born on October 20, 1950 in Florida. He had a rough childhood and did not do well in school, according to the New York Times. He caught the rock‘n‘roll bug after he was introduced by his uncle to Elvis Presley, who was shooting the picture “Follow That Dream” on location in Florida in 1960.

Petty was both a musician and obsessive fan, one who met his childhood heroes and lived out the fantasies of countless young rock lovers. He befriended Byrds leader Roger McGuinn and became close to George Harrison. Petty inducted Harrison into the Rock Hall in 2004; two years earlier Dylan’s son Jakob inducted Petty. In the 1980s, Petty and the Heartbreakers supported Bob Dylan on a nationwide tour.

He would speak of being consumed by rock music since childhood, to the point where his father, whom Petty would later say beat him savagely, thought he was “mental.” Awed by the chiming guitars of the Byrds, the melodic genius of the Beatles and the snarling lyrics of Dylan, he was amazed to find that other kids were feeling the same way.

“You’d go and see some other kid whose hair was long, this was around ’65, and go, ‘Wow, there’s one like me,'” he told The Associated Press in 1989. “You’d go over and talk and he’d say, ‘I’ve got a drum set.’ ‘You do? Great!’ That was my whole life.”

By his early 20s, Petty had formed the group Mudcrutch with fellow Gainesville natives and future Heartbreakers (guitarist) Mike Campbell and (keyboardist) Benmont Tench. They soon broke up, but reunited in Los Angeles as the Heartbreakers, joined by bassist Ron Blair and drummer Stan Lynch. Their eponymous debut album came out in 1976 and they soon built a wide following, fitting easily into the New Wave sounds of the time.

The world changed more than Petty did over the past few decades. In 2014, around the time he received an ASCAP Founders Award, he told The Associated Press that he thought of himself as “kind of a music historian.”

“I’m always interested in the older music, and I’m still always discovering things that I didn’t know about,” he said. “To be honest, I really probably spend more time listening to the old stuff than I do the new stuff.”

Amid his successes, Petty also suffered dark periods during a career spanning five decades.

A 2015 biography of the singer, “Petty: The Biography,” revealed for the first time the rocker’s heroin addiction in the 1990s.

Author Warren Zanes said in an interview with The Washington Post that Petty had succumbed to the drug because he “had had encounters with people who did heroin, and he hit a point in his life when he did not know what to do with the pain he was feeling”.

Petty also suffered from depression, channeling his pain into 1999’s “Echo,” during which he was also dealing with a divorce. In 2002, he married Dana York and told Reuters that he had been in therapy for six years to deal with depression.

“It’s a funny disease because it takes you a long time to really come to terms with the fact that you’re sick – medically sick, you’re not just suddenly going out of your mind,” he said at the time.